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  • The FDA announced the approval of your new fat loss drug on Sept. 11, 2014. The drug name is Contrave.

    Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err on the side of caution and allow the FDA do its job and demand some study be done in order that the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on their own medications.

    Researchers found out that participants taking this drug for the year, lost weight within a month and have kept the extra weight off through the entire 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of many active ingredient, which might make them far better and safer.

    Combo-pilling will be the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that since right now there are not any long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug also can raise blood pressure levels and heart rate, and mustn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise hypertension and heartrate and must not used in patients with uncontrolled high blood pressure, and also by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

    Suboxone includes two drugs; buprenorphine and naloxone. The naloxone is irrelevant if your addict uses the medication properly, but when the tablet is dissolved in water and injected the naloxone can cause instant withdrawal. When suboxone can be used correctly, the naloxone is destroyed inside liver after that uptake through the intestines and has no therapeutic effect. Buprenorphine is the active substance; it is absorbed underneath the tongue (and during the entire mouth) but destroyed through the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I manipulate this formulation once the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have also treated addicts who may have had gastric bypass, where the first section of the intestine is bypassed and the stomach contents empty right into a more distal the main small intestine. In such cases the naloxone escapes ?first pass metabolism', the process with normal anatomy the place that the drug is taken up from the duodenum and transferred right to the liver with the portal vein, where it's quickly and completely destroyed. After gastric bypass naloxone can be taken on by portions of the intestine which are not served by the portal system, causing blood levels of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.

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